Latest group publications- TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages 17 November 2020 Hazel Hall-Roberts
- Interferon-stimulated gene products as regulators of central carbon metabolism 13 November 2020 Kourosh H Ebrahimi
- Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 16 October 2020 Jiangdong Huo
- A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy 18 August 2020 Xiaoniu Miao
- Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication 9 August 2020 Helene Borrmann
- Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient 2 August 2020 Daming Zhou
- ADAM17-triggered TNF signalling protects the ageing Drosophila retina from lipid droplet-mediated degeneration 28 July 2020 Sonia Muliyil
- Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 15 July 2020 Jiangdong Huo
- Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening 11 July 2020 Simon Gutbier
- Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs 1 July 2020 Benjamin T Dodsworth
Author Archives: William James
PhD op[portunity, see: https://www.findaphd.com/phds/project/exploring-parkinson-s-related-gene-function-in-hips-macrophages-and-microglia/?p66609
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Stem Cell Schools’ workshop
We worked with Science Oxford to show year 10 pupils from three Oxfordshire state schools something about the biology and potential of stem cells. See the video of the event at Voices from Oxford.
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PhD Project 2018: Investigating the biology of human tissue macrophages in health and disease
Apply here: https://www.findaphd.com/search/ProjectDetails.aspx?PJID=66609&LID=1238 Project Description Macrophages, such as the microglia of the brain, play essential homeostatic, remodelling, recycling and defence functions in all the tissues of the body. When they are overwhelmed by specialized pathogens such as HIV-1, or chronic accumulations … Continue reading
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Protection of HIV neutralizing aptamers against rectal and vaginal nucleases: Implications for RNA-based therapeutics
Author(s):Moore, M.D. | Cookson, J. | Coventry, V.K. | Sproat, B. | Rabe, L. | Cranston, R.D. | McGowan, I. | James, W.Publication year: 2011Journal / Book title: Journal of Biological Chemistry Access all results for your search in Scopus … Continue reading
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Efficient, Long Term Production of Monocyte-Derived Macrophages from Human Pluripotent Stem Cells under Partly-Defined and Fully-Defined Conditions
Author(s):van Wilgenburg, B. | Browne, C. | Vowles, J. | Cowley, S.A.Publication year: 2013Journal / Book title: PLoS ONE Access all results for your search in Scopus …read more Source:: cowley, sally a.” 7102482900 “james, william s.” 35479049300 “moore, michael … Continue reading
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Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration
Author(s):Zhou, L. | Sokolskaja, E. | Jolly, C. | James, W. | Cowley, S.A. | Fassati, A.Publication year: 2011Journal / Book title: PLoS Pathogens Access all results for your search in Scopus …read more Source:: “james, william s.” 35479049300
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CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells
Author(s):Flynn, R. | Grundmann, A. | Renz, P. | Hänseler, W. | James, W.S. | Cowley, S.A. | Moore, M.D.Publication year: 2015Journal / Book title: Experimental Hematology Access all results for your search in Scopus …read more Source:: cowley, sally … Continue reading
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Multiplex High-Throughput Targeted Proteomic Assay to Identify Induced Pluripotent Stem Cells
Author(s):Baud, A. | Wessely, F. | Mazzacuva, F. | McCormick, J. | Camuzeaux, S. | Heywood, W.E. | Little, D. | Vowles, J. | Tuefferd, M. | Mosaku, O. | Lako, M. | Armstrong, L. | Webber, C. | Cader, … Continue reading
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MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons
Author(s):Beevers, J.E. | Lai, M.C. | Collins, E. | Booth, H.D.E. | Zambon, F. | Parkkinen, L. | Vowles, J. | Cowley, S.A. | Wade-Martins, R. | Caffrey, T.M.Publication year: 2017Journal / Book title: Stem Cell Reports Access all results … Continue reading
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Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson’s disease
Author(s):Sandor, C. | Robertson, P. | Lang, C. | Heger, A. | Booth, H. | Vowles, J. | Witty, L. | Bowden, R. | Hu, M. | Cowley, S.A. | Wade-Martins, R. | Webber, C.Publication year: 2017Journal / Book title: … Continue reading
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