Latest group publications- The use of nanobodies in a sensitive ELISA test for SARS-CoV-2 Spike 1 protein 11 October 2021 Georgina C Girt
- Variation on a theme: mapping microglial heterogeneity 26 September 2021 Sam J Washer
- A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19 23 September 2021 Jiandong Huo
- Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern 18 August 2021 Donal T Skelly
- Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress 31 July 2021 Luiza Mendonça
- Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium 25 June 2021 Alun Vaughan-Jackson
- Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism 28 May 2021 Justyna Okarmus
- Geographical distribution of fertility rates in 70 low-income, lower-middle-income, and upper-middle-income countries, 2010-16: a subnational analysis of cross-sectional surveys 21 May 2021 Carla Pezzulo
- Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism 20 May 2021 Joanne Ng
- Non-neuronal cells in amyotrophic lateral sclerosis - from pathogenesis to biomarkers 30 April 2021 Björn F Vahsen
Maria Karabova
DPhil Student | Lincoln College | maria.karabova@path.ox.ac.uk
I am a DPhil student sponsored by the Oxford-E P Abraham Graduate Scholarship. My primary interest lies in the molecular pathology of Alzheimer’s disease. Currently, I am studying the processing of tau-protein aggregates by human iPSc-derived macrophages and microglia.
My academic journey started with a detour in medicine. During the studies, however, I realized that the methods and medication available, particularly with regards to the diseases of the brain, can often leave doctors applying plasters to gunshot wounds. A search for real advancements in the way we treat brain disorders led me to science. I completed my neuroscience training at the King’s College London in 2018 with a year in Industry at the UCI MIND Institute in California, USA. There, under the mentorship and supervision from Prof Carl Cotman, I worked on several projects, including the investigation of IL12/23-induced modulation of synaptic plasticity, elucidation of effective exercise patterns for long-term memory formation, and targeting H3K9me3 for treatment of cognitive decline associated with ageing and Alzheimer’s disease. Our work on the effect of early-life exercise on late-life cognitive reserve received the Gold Award in STEM for Britain 2018.