Yueming Ren | Research Assistant

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I joined the James Lab as a Research Assistant in September 2023. My research focus on innate immune response mediated through the DNA-sensing cGAS-STING pathway in iPS-derived models of Parkinson’s Disease. I am interested in the molecular mechanisms of neuroinflammation and the crosstalk between neurons, microglia and astrocytes in neurodegenerative diseases. Particularly, my work aims to investigate how cGAS-STING pathway exacerbates neuroinflammation in patients with PINK/Parkin mutations.

I obtained a Bachelor of Biomedicine (first class honours) from University of Melbourne. I then joined Prof Wenbin Zeng’s lab in Central South University, China to develop novel photosensitive therapeutic agents before coming here to Oxford to study for MSc in Pharmacology. I did my MSc research project under the supervision of Dr Sally Cowley where I investigated cGAS-STING mediated IL-6 release from iPS-derived microglia. I was awarded the Stutchbury prize for highest ranking MSc student undertaking one-year MSc Course in Pharmacology.

Outside the lab, you would most likely catch me searching for new recipes and cooking 😀